Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20212179 | 1.00 | NPSR1 (0.51) | NPSR1SLC6A4TLR7DHFR | |
| SCHEMBL6120485 | 0.91 | NPSR1 (0.51) | NPSR1SLC6A4TLR7 | |
| SCHEMBL30037440 | 0.86 | TLR7 (0.43) | TLR7DHFR | |
| SCHEMBL20212196 | 0.86 | TLR7 (0.43) | TLR7DHFR | |
| SCHEMBL2869870 | 0.84 | NPSR1 (0.55) | NPSR1TLR7DHFR | |
| SCHEMBL20212148 | 0.82 | TLR7 (0.50) | NPSR1TLR7 | |
| SCHEMBL30036063 | 0.82 | NPSR1 (0.54) | NPSR1TLR7 | |
| SCHEMBL20212293 | 0.82 | NPSR1 (0.54) | NPSR1TLR7 | |
| SCHEMBL20223072 | 0.80 | NPSR1 (0.52) | NPSR1TLR7 | |
| SCHEMBL20212262 | 0.80 | NPSR1 (0.58) | NPSR1TLR7DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177780-B | Pyrimidine compounds containing acidic groups | 阿普罗斯治疗公司 | 2022-11-01 | — | — | CN | disclosed |