SCHEMBL3003737

SCHEMBL3003737

CC(C)(C)c1ccc(OP(OF)Oc2ccc(C(C)(C)C)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.39
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
APEX1 P27695 1/20 0.35
KDM4E B2RXH2 3/20 0.34
KIF11 P52732 1/20 0.34
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
ALOX15 P16050 2/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 2/20 0.33
CYP2C19 P33261 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RECQL P46063 2/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8390533 0.97 CA1 (0.37) KCNH2CA1CA2CA9APEX1
SCHEMBL9512517 0.92 KCNH2 (0.38) KCNH2CA1CA2CA9APEX1
SCHEMBL10413319 0.90 APEX1 (0.33) KCNH2CA1CA2CA9APEX1
SCHEMBL29349873 0.89 CA1 (0.41) KCNH2CA1CA2CA9APEX1
SCHEMBL26607 0.89 CA1 (0.41) KCNH2CA1CA2CA9APEX1
SCHEMBL10699196 0.89 APEX1 (0.33) KCNH2CA1CA2CA9APEX1
Phosphine SCHEMBL7943984 0.87 CA1 (0.40) KCNH2CA1CA2CA9APEX1
Potassium SCHEMBL31621706 0.87 CA1 (0.40) KCNH2CA1CA2CA9APEX1
SCHEMBL5608973 0.87 CA1 (0.40) KCNH2CA1CA2CA9APEX1
SCHEMBL19514039 0.87 CA1 (0.40) KCNH2CA1CA2CA9APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE36128-E STABILIZER FOR ORGANIC COMPOUNDS ALBEMARLE CORPORATION (US) 1999-03-02 US claimed
EP-0280938-B1 Antioxidant aromatic fluorophosphites ETHYL CORP (US) 1994-06-15 EP claimed
EP-0301355-B1 Aqueous aryl fluorophosphite suspension ETHYL CORP (US) 1993-12-29 EP claimed
US-4912155-A Containing substituted aryl group ETHYL CORPORATION (US) 1990-03-27 US claimed
US-4867907-A POLYMER STABILIZERS ETHYL CORPORATION (US) 1989-09-19 US claimed
EP-0301355-A2 Aqueous aryl fluorophosphite suspension ETHYL CORPORATION (US) 1989-02-01 EP claimed
EP-0280938-A1 Antioxidant aromatic fluorophosphites ALBEMARLE CORPORATION (US) 1988-09-07 EP claimed
CN-107109236-B Fire retardant combination and flame-retarded synthetic resin composition 株式会社艾迪科 2019-03-08 CN disclosed
US-20100190898-A1 Weakly Basic Hindered Amines Compounds Having Carbonate Skeletons, Synthetic Resin Compositions And Coating Compositions NEGISHI YOSHINORI 2010-07-29 US disclosed
EP-0926189-B1 A macromolecular material composition and a modifier for macromolecular material HITACHI CHEMICAL CO LTD (JP) 2004-04-14 EP disclosed
EP-1017494-B1 HYDROFORMYLATION PROCESS USING NOVEL PHOSPHITE-METAL CATALYST SYSTEM EASTMAN CHEM CO (US) 2004-01-21 EP disclosed
EP-1017494-A1 HYDROFORMYLATION PROCESS USING NOVEL PHOSPHITE-METAL CATALYST SYSTEM EASTMAN CHEMICAL COMPANY (US) 2000-07-12 EP disclosed
EP-0926189-A2 A macromolecular material composition and a modifier for macromolecular material HITACHI CHEMICAL CO., LTD. (JP) 1999-06-30 EP disclosed
EP-0280938-B1 Antioxidant aromatic fluorophosphites ETHYL CORP (US) 1994-06-15 EP disclosed
EP-0301355-B1 Aqueous aryl fluorophosphite suspension ETHYL CORP (US) 1993-12-29 EP disclosed
US-4958034-A DISCOLORATION INHIBITION; REACTION OF OLEFIN AND MALEIC ANHYDRIDE IN ARYLFLUOROPHOSPHITE PRESENCE ETHYL CORPORATION (US) 1990-09-18 US disclosed
US-4912155-A Containing substituted aryl group ETHYL CORPORATION (US) 1990-03-27 US disclosed
US-4867907-A POLYMER STABILIZERS ETHYL CORPORATION (US) 1989-09-19 US disclosed
EP-0301355-A2 Aqueous aryl fluorophosphite suspension ETHYL CORPORATION (US) 1989-02-01 EP disclosed
EP-0280938-A1 Antioxidant aromatic fluorophosphites ALBEMARLE CORPORATION (US) 1988-09-07 EP disclosed