SCHEMBL30037437

SCHEMBL30037437

CCCCNc1nc(N)nc(C)c1Cc1cc(CP(=O)(O)O)ccc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20212200 1.00 TLR7 (1.00) TLR7
SCHEMBL20223043 0.92 TLR7 (0.85) TLR7
SCHEMBL159189 0.90 TLR7 (0.82) TLR7
SCHEMBL21475792 0.89 TLR7 (0.81) TLR7
SCHEMBL31410733 0.89 TLR7 (0.81) TLR7
SCHEMBL30037544 0.89 TLR7 (0.81) TLR7
SCHEMBL20212158 0.88 TLR7 (0.81) TLR7
SCHEMBL4198169 0.87 TLR7 (0.86) TLR7
SCHEMBL20212172 0.87 TLR7 (1.00) TLR7
SCHEMBL2849003 0.87 TLR7 (1.00) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110177780-B Pyrimidine compounds containing acidic groups 阿普罗斯治疗公司 2022-11-01 CN disclosed