Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162774 | 1.00 | CFTR (0.59) | CFTR | |
| SCHEMBL28873353 | 0.94 | CFTR (0.52) | CFTR | |
| SCHEMBL29768981 | 0.86 | CFTR (0.59) | CFTR | |
| SCHEMBL20162681 | 0.86 | CFTR (0.59) | CFTR | |
| SCHEMBL20162726 | 0.86 | CFTR (0.49) | CFTR | |
| SCHEMBL30037914 | 0.86 | CFTR (0.49) | CFTR | |
| SCHEMBL20162778 | 0.82 | CFTR (0.60) | CFTR | |
| SCHEMBL20162703 | 0.82 | CFTR (0.60) | CFTR | |
| SCHEMBL30038301 | 0.82 | CFTR (0.60) | CFTR | |
| SCHEMBL30037553 | 0.82 | CFTR (0.60) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4424311-A2 | PYRROLOPYRIMIDINES AS CFTR POTENTIATORS | Cystic Fibrosis Foundation (US) | 2024-09-04 | — | — | EP | claimed |
| CN-115850268-A | Pyrrolopyrimidines as CFTR potentiators | 囊性纤维化基金会 | 2023-03-28 | — | — | CN | claimed |
| EP-4424311-A2 | PYRROLOPYRIMIDINES AS CFTR POTENTIATORS | Cystic Fibrosis Foundation (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-115850268-A | Pyrrolopyrimidines as CFTR potentiators | 囊性纤维化基金会 | 2023-03-28 | — | — | CN | disclosed |
| CN-110337294-B | Pyrrolopyrimidines as CFTR potentiators | 囊性纤维化基金会 | 2022-11-01 | — | — | CN | disclosed |