Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 19/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21500459 | 1.00 | HDAC11 (1.00) | HDAC11HDAC6HDAC8 | |
| Hydrochloric Acid SCHEMBL30038176 | 0.99 | HDAC11 (0.98) | HDAC11HDAC6HDAC8 | |
| SCHEMBL30040214 | 0.84 | HDAC11 (0.72) | HDAC11HDAC6HDAC8 | |
| SCHEMBL21500498 | 0.84 | HDAC11 (0.72) | HDAC11HDAC6HDAC8 | |
| SCHEMBL21496690 | 0.81 | HDAC11 (0.73) | HDAC11HDAC6HDAC8 | |
| SCHEMBL25932103 | 0.81 | HDAC11 (0.76) | HDAC11HDAC6HDAC8 | |
| SCHEMBL30038158 | 0.81 | HDAC11 (1.00) | HDAC11HDAC6HDAC8 | |
| SCHEMBL21500450 | 0.81 | HDAC11 (1.00) | HDAC11HDAC6HDAC8 | |
| SCHEMBL21496713 | 0.79 | HDAC11 (0.77) | HDAC11HDAC6HDAC8 | |
| SCHEMBL30039411 | 0.79 | HDAC11 (0.77) | HDAC11HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535607-B2 | Isoindolines as HDAC inhibitors | VALO HEALTH, INC. (US) | 2022-12-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11535607-B2 | Isoindolines as HDAC inhibitors | HDAC1, HDAC2, HDAC3 | HDAC11 4/4885HDAC6 8/4885HDAC8 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.