SCHEMBL30040647

SCHEMBL30040647

O=C(NC1CCCC1)c1ccnc(-n2ccnc2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CD38 P28907 20/20 1.00
▸ CYP2D6 P10635 1/20 0.76
▸ CYP2B6 P20813 1/20 0.76
▸ CYP2C19 P33261 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30040534 0.99 CD38 (1.00) CD38CYP2D6CYP2B6CYP2C19
SCHEMBL25489728 0.99 CD38 (1.00) CD38CYP2D6CYP2B6CYP2C19
SCHEMBL30040515 0.99 CD38 (1.00) CD38CYP2D6CYP2B6CYP2C19
SCHEMBL25135925 0.91 CD38 (0.83) CD38CYP2D6CYP2B6CYP2C19
SCHEMBL25135870 0.91 CD38 (0.83) CD38CYP2D6CYP2B6CYP2C19
SCHEMBL29182237 0.90 CD38 (1.00) CD38CYP2D6CYP2B6CYP2C19
SCHEMBL25136138 0.90 CD38 (1.00) CD38CYP2D6CYP2B6CYP2C19
SCHEMBL30040406 0.90 CD38 (1.00) CD38CYP2D6CYP2B6CYP2C19
SCHEMBL30723426 0.88 CD38 (0.78) CD38CYP2D6CYP2B6CYP2C19
SCHEMBL25135955 0.88 CD38 (1.00) CD38CYP2D6CYP2B6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254113-A1 COMPOUNDS AND THEIR USES AS CD38 INHIBITORS Nanjing Immunophage Biotech Co., Ltd. (CN) 2024-08-01 — — US claimed
WO-2022228496-A1 COMPOUNDS AND THEIR USES AS CD38 INHIBITORS NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) 2022-11-03 — — WO claimed
US-20250382283-A1 COMPOUNDS AND THEIR USES AS CD38 INHIBITORS NANJING IMMUNOPHAGE BIOTECH CO LTD (CN) 2025-12-18 — — US disclosed
US-20240254113-A1 COMPOUNDS AND THEIR USES AS CD38 INHIBITORS Nanjing Immunophage Biotech Co., Ltd. (CN) 2024-08-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254113-A1 COMPOUNDS AND THEIR USES AS CD38 INHIBITORS CD38, CD22, BCL6B CD38 1/4885CYP2D6 2636/4885CYP2B6 3442/4885
US-20250382283-A1 COMPOUNDS AND THEIR USES AS CD38 INHIBITORS CD38, FCGRT, CD22 CD38 1/4885CYP2D6 2674/4885CYP2B6 3578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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