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SCHEMBL30041224

SCHEMBL30041224

O=C(O)C1=C[C@H](O)[C@@H](OS(=O)(=O)O)[C@H](O[C@H]2[C@H](O)[C@@H](NS(=O)(=O)O)[C@@H](O[C@H]3[C@H](O)[C@@H](OS(=O)(=O)O)[C@H](O[C@H]4[C@H](O)[C@@H](NS(=O)(=O)O)[C@@H](O[C@H]5[C@H](O)[C@@H](OS(=O)(=O)O)[C@H](O[C@H]6[C@H](O)[C@@H](NS(=O)(=O)O)[C@@H](O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@H]8[C@H](O)[C@@H](NS(=O)(=O)O)[C@@H](O[C@H]9[C@H](O)[C@@H](OS(=O)(=O)O)[C@H](O[C@H]%10[C@H](O)[C@@H](NS(=O)(=O)O)[C@@H](O)O[C@@H]%10COS(=O)(=O)O)O[C@H]9C(=O)O)O[C@@H]8COS(=O)(=O)O)O[C@@H]7C(=O)O)O[C@@H]6COS(=O)(=O)O)O[C@H]5C(=O)O)O[C@@H]4COS(=O)(=O)O)O[C@H]3C(=O)O)O[C@@H]2COS(=O)(=O)O)O1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 3/20 0.64
▸ SERPINC1 P01008 2/20 0.46
▸ F2 P00734 1/20 0.46
▸ BDNF P23560 3/20 0.42
▸ PTN P21246 2/20 0.42
▸ MDK P21741 2/20 0.42
▸ HPSE Q9Y251 7/20 0.40
▸ CCL2 P13500 2/20 0.38
▸ CXCL12 P48061 2/20 0.38
▸ PF4 P02776 2/20 0.38
▸ IFNG P01579 1/20 0.38
▸ BMP2 P12643 1/20 0.38
▸ VEGFA P15692 1/20 0.38
▸ SELP P16109 1/20 0.38
▸ BMP6 P22004 1/20 0.38
▸ CCL11 P51671 1/20 0.38
▸ WNT3A P56704 1/20 0.38
▸ SELPLG Q14242 1/20 0.38
▸ SHH Q15465 1/20 0.38
▸ CXCL10 P02778 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29647566 0.98 F10 (0.60) F10SERPINC1F2BDNFPTN
SCHEMBL12300300 0.91 F10 (0.63) F10SERPINC1F2BDNFPTN
SCHEMBL15395282 0.91 F10 (0.57) F10SERPINC1F2BDNFPTN
SCHEMBL12532633 0.89 F10 (0.64) F10SERPINC1F2BDNFPTN
SCHEMBL29941441 0.89 F10 (0.46) F10SERPINC1F2BDNFPTN
SCHEMBL15395197 0.89 F10 (0.46) F10SERPINC1F2BDNFPTN
SCHEMBL15395243 0.88 F10 (0.56) F10SERPINC1F2BDNFPTN
SCHEMBL29352252 0.88 F10 (0.56) F10SERPINC1F2BDNFPTN
SCHEMBL29358293 0.88 F10 (0.56) F10SERPINC1F2BDNFPTN
SCHEMBL29399157 0.88 F10 (0.56) F10SERPINC1F2BDNFPTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4093509-A1 SULFONIMIDAMIDE COMPOUNDS AS NLRP3 MODULATORS F. Hoffmann-La Roche AG (CH) 2022-11-30 — — EP claimed
EP-3149143-B1 USE OF POLYPEPTIDE NOVOZYMES AS (DK) 2025-08-06 — — EP disclosed
EP-4373826-A1 SULFONIMIDAMDE COMPOUNDS AND USES THEREOF Genentech, Inc. (US) 2024-05-29 — — EP disclosed
CN-117315117-A High-realism nerve rendering method based on diffusion model 北京理工大学 2023-12-29 — — CN disclosed
WO-2023004257-A1 SULFONIMIDAMDE COMPOUNDS AND USES THEREOF GENENTECH, INC. (US) 2023-01-26 — — WO disclosed
EP-4093509-A1 SULFONIMIDAMIDE COMPOUNDS AS NLRP3 MODULATORS F. Hoffmann-La Roche AG (CH) 2022-11-30 — — EP disclosed
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