SCHEMBL30041333

SCHEMBL30041333

c1ccc(N2CCN(Cc3cc4ccccc4[nH]3)CC2)nc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 8/20 0.77
DRD2 P14416 5/20 0.77
DRD3 P35462 4/20 0.77
OPRK1 P41145 2/20 0.77
HTR1A P08908 1/20 0.77
ADRA2A P08913 1/20 0.77
ADRA2B P18089 1/20 0.77
ADRA2C P18825 1/20 0.77
HRH4 Q9H3N8 1/20 0.61
ALDH1A1 P00352 3/20 0.61
KDM4E B2RXH2 2/20 0.61
CYP3A4 P08684 1/20 0.61
ALOX15 P16050 1/20 0.61
SIGMAR1 Q99720 1/20 0.61
KMT2A Q03164 2/20 0.58
MAPT P10636 2/20 0.57
CHIA Q9BZP6 1/20 0.57
RAB9A P51151 1/20 0.52
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6786631 1.00 DRD4 (0.77) DRD4DRD2DRD3OPRK1HTR1A
SCHEMBL11328651 0.88 DRD4 (0.64) DRD4DRD2DRD3OPRK1HTR1A
SCHEMBL4814827 0.87 DRD4 (1.00) DRD4DRD2DRD3OPRK1HTR1A
SCHEMBL23964222 0.86 DRD4 (0.60) DRD4DRD2DRD3OPRK1HTR1A
SCHEMBL28962380 0.86 DRD4 (0.65) DRD4DRD2DRD3OPRK1HTR1A
SCHEMBL4823457 0.86 DRD4 (0.65) DRD4DRD2DRD3OPRK1HTR1A
SCHEMBL28962388 0.84 DRD4 (0.72) DRD4DRD2DRD3OPRK1HTR1A
SCHEMBL4817050 0.83 DRD4 (0.92) DRD4DRD2DRD3OPRK1HTR1A
SCHEMBL23964347 0.81 HRH4 (0.60) DRD4DRD2DRD3OPRK1HTR1A
SCHEMBL30041015 0.81 HRH4 (0.60) DRD4DRD2DRD3OPRK1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
EP-4139291-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-03-01 EP disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed