SCHEMBL30041365

SCHEMBL30041365

CCc1cncnc1N1CCN(Cc2cc3ccccc3[nH]2)CC1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RPS6KB1 P23443 1/20 0.55
HRH4 Q9H3N8 1/20 0.55
DRD2 P14416 11/20 0.44
DRD3 P35462 11/20 0.44
DRD4 P21917 3/20 0.44
HTR1A P08908 1/20 0.44
ADRA2A P08913 1/20 0.44
ADRA2B P18089 1/20 0.44
ADRA2C P18825 1/20 0.44
OPRK1 P41145 1/20 0.44
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
PARP1 P09874 1/20 0.41
HCRTR1 O43613 1/20 0.40
HCRTR2 O43614 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23964232 0.87 HRH4 (0.57) RPS6KB1HRH4DRD2DRD3DRD4
SCHEMBL23964271 0.87 RPS6KB1 (0.53) RPS6KB1HRH4DRD2DRD3DRD4
SCHEMBL30040691 0.87 RPS6KB1 (0.53) RPS6KB1HRH4DRD2DRD3DRD4
SCHEMBL30041737 0.85 HRH4 (0.48) RPS6KB1HRH4DRD2DRD3DRD4
SCHEMBL23964190 0.85 HRH4 (0.48) RPS6KB1HRH4DRD2DRD3DRD4
SCHEMBL23964270 0.85 RPS6KB1 (0.51) RPS6KB1HRH4DRD2DRD3DRD4
SCHEMBL30040140 0.85 HRH4 (0.54) HRH4DRD2DRD3DRD4HTR1A
SCHEMBL23932592 0.85 HRH4 (0.54) HRH4DRD2DRD3DRD4HTR1A
SCHEMBL23964196 0.84 HRH4 (0.54) HRH4DRD2DRD3DRD4HTR1A
SCHEMBL30041187 0.84 HRH4 (0.54) HRH4DRD2DRD3DRD4HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
EP-4139291-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-03-01 EP disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed