SCHEMBL30041985

SCHEMBL30041985

c1ccc2c(c1)ccn2CN1CCNCC1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 4/20 0.52
CCND1 P24385 4/20 0.52
KMT2A Q03164 1/20 0.44
SIGMAR1 Q99720 1/20 0.43
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
HTR6 P50406 4/20 0.42
SLC6A4 P31645 1/20 0.42
P2RX7 Q99572 1/20 0.42
PRMT5 O14744 1/20 0.42
RAD52 P43351 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3205958 1.00 CDK4 (0.52) CDK4CCND1KMT2ASIGMAR1HTR2A
SCHEMBL11012058 0.85 CDK4 (0.65) CDK4CCND1SIGMAR1HTR2AHTR2C
SCHEMBL4828100 0.84 CDK4 (0.57) CDK4CCND1KMT2AHTR2AHTR2C
SCHEMBL7052509 0.84 CDK4 (0.57) CDK4CCND1KMT2AHTR2AHTR2C
SCHEMBL4896448 0.83 CDK4 (0.55) CDK4CCND1KMT2AHTR2AHTR2C
SCHEMBL15578543 0.83 CDK4 (0.67) CDK4CCND1SIGMAR1HTR2AHTR2C
SCHEMBL3205345 0.80 CDK4 (0.56) CDK4CCND1SIGMAR1HTR2AHTR2C
SCHEMBL5944315 0.80 CDK4 (0.52) CDK4CCND1KMT2AHTR2AHTR2C
Hydrochloric Acid SCHEMBL28867138 0.79 CDK4 (0.55) CDK4CCND1SIGMAR1HTR2AHTR2C
Ammonia Solution, Strong SCHEMBL28783985 0.79 CDK4 (0.55) CDK4CCND1SIGMAR1HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed