⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5485105 | 0.70 | — | — | |
| SCHEMBL5485107 | 0.70 | — | — | |
| Thiophene SCHEMBL28066484 | 0.68 | — | — | |
| SCHEMBL16393728 | 0.67 | — | — | |
| SCHEMBL29793022 | 0.67 | — | — | |
| SCHEMBL7882964 | 0.65 | — | — | |
| SCHEMBL815394 | 0.65 | — | — | |
| SCHEMBL814493 | 0.65 | — | — | |
| Lithium SCHEMBL30018240 | 0.65 | — | — | |
| SCHEMBL3512223 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093509-A1 | SULFONIMIDAMIDE COMPOUNDS AS NLRP3 MODULATORS | F. Hoffmann-La Roche AG (CH) | 2022-11-30 | — | — | EP | disclosed |