Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 15/20 | 1.00 |
| ▸ | IKBKB | O14920 | 4/20 | 0.68 |
| ▸ | CHUK | O15111 | 4/20 | 0.68 |
| ▸ | AKT1 | P31749 | 4/20 | 0.68 |
| ▸ | AKT2 | P31751 | 4/20 | 0.68 |
| ▸ | AKT3 | Q9Y243 | 4/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19863741 | 1.00 | PADI4 (1.00) | PADI4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL23497993 | 1.00 | PADI4 (1.00) | PADI4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL19857822 | 0.96 | PADI4 (0.92) | PADI4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL19863734 | 0.93 | PADI4 (0.87) | PADI4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL19857753 | 0.92 | PADI4 (0.85) | PADI4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL19857844 | 0.92 | PADI4 (0.85) | PADI4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL19857756 | 0.92 | PADI4 (0.85) | PADI4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL19857761 | 0.92 | PADI4 (0.85) | PADI4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL19863753 | 0.90 | PADI4 (0.82) | PADI4IKBKBCHUKAKT1AKT2 | |
| SCHEMBL19857786 | 0.90 | PADI4 (0.82) | PADI4IKBKBCHUKAKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4073054-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF TUMORS | Fondazione Istituto Italiano di Tecnologia (IT) | 2022-10-19 | — | — | EP | disclosed |