Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | TEC | P42680 | 1/20 | 0.42 |
| ▸ | TXK | P42681 | 1/20 | 0.42 |
| ▸ | BLK | P51451 | 1/20 | 0.42 |
| ▸ | BMX | P51813 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23605794 | 1.00 | BTK (0.58) | BTKEGFRERBB2TECTXK | |
| SCHEMBL23605867 | 0.89 | BTK (0.58) | BTK | |
| SCHEMBL30406999 | 0.89 | BTK (0.58) | BTK | |
| SCHEMBL30407796 | 0.88 | BTK (0.59) | BTKEGFRERBB2TECTXK | |
| SCHEMBL23605851 | 0.88 | BTK (0.59) | BTKEGFRERBB2TECTXK | |
| SCHEMBL23605666 | 0.87 | BTK (0.58) | BTKEGFRERBB2TECTXK | |
| SCHEMBL30044532 | 0.87 | BTK (0.56) | BTKEGFRERBB2TECTXK | |
| SCHEMBL23605865 | 0.87 | BTK (0.56) | BTKEGFRERBB2TECTXK | |
| SCHEMBL23605813 | 0.86 | BTK (0.51) | BTK | |
| SCHEMBL30044972 | 0.86 | BTK (0.51) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081514-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2022-11-02 | — | — | EP | disclosed |