Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23605583 | 1.00 | EPHX2 (0.42) | EPHX2MGLLGRIN2BPOLBLMNA | |
| SCHEMBL23577554 | 0.88 | EPHX2 (0.42) | EPHX2MGLLGRIN2BHPGDMEN1 | |
| SCHEMBL30045021 | 0.87 | HCRTR1 (0.42) | EPHX2MGLLGRIN2BPOLBLMNA | |
| SCHEMBL23605587 | 0.87 | HCRTR1 (0.42) | EPHX2MGLLGRIN2BPOLBLMNA | |
| SCHEMBL23605707 | 0.86 | HCRTR1 (0.56) | MGLLLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL29844096 | 0.85 | EPHX2 (0.43) | EPHX2POLBLMNAHPGDSMN1; SMN2 | |
| SCHEMBL23605155 | 0.85 | EPHX2 (0.43) | EPHX2POLBLMNAHPGDSMN1; SMN2 | |
| SCHEMBL30044850 | 0.84 | EPHX2 (0.38) | EPHX2MGLLPOLBLMNAHPGD | |
| SCHEMBL30044957 | 0.84 | EPHX2 (0.38) | EPHX2MGLLPOLBLMNAHPGD | |
| SCHEMBL30045060 | 0.84 | EPHX2 (0.40) | EPHX2MGLLPOLBLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081509-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | Zydus Lifesciences Limited (IN) | 2022-11-02 | — | — | EP | disclosed |