Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.55 |
| ▸ | CNR2 | P34972 | 11/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300459 | 0.95 | CNR2 (0.51) | CNR1CNR2KDM4EMEN1CYP1A2 | |
| SCHEMBL3156288 | 0.93 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL300358 | 0.93 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL300532 | 0.88 | CNR1 (0.52) | CNR1CNR2CYP2C9GPR55 | |
| SCHEMBL3153456 | 0.88 | CNR1 (0.54) | CNR1CNR2 | |
| SCHEMBL176716 | 0.88 | CNR1 (0.66) | CNR1CNR2KDM4EMEN1CYP1A2 | |
| SCHEMBL176717 | 0.88 | CNR1 (0.66) | CNR1CNR2KDM4EMEN1CYP1A2 | |
| SCHEMBL13871590 | 0.87 | CNR1 (0.65) | CNR1CNR2KDM4EMEN1CYP1A2 | |
| SCHEMBL300686 | 0.84 | CNR1 (0.55) | CNR1CNR2CYP2C9GPR55 | |
| SCHEMBL4712170 | 0.83 | CNR1 (0.47) | CNR1CNR2CYP2C9GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |