Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 9/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23857033 | 1.00 | NR3C2 (0.46) | NR3C2NR3C1KCNH2 | |
| SCHEMBL23857162 | 0.81 | NR3C2 (0.47) | NR3C2NR3C1KCNH2 | |
| SCHEMBL30048400 | 0.81 | NR3C2 (0.47) | NR3C2NR3C1KCNH2 | |
| SCHEMBL30253108 | 0.79 | NR3C2 (0.45) | NR3C2NR3C1KCNH2 | |
| SCHEMBL23857656 | 0.79 | NR3C2 (0.45) | NR3C2NR3C1KCNH2 | |
| SCHEMBL23871559 | 0.78 | NR3C2 (0.47) | NR3C2NR3C1KCNH2 | |
| Hydrochloric Acid SCHEMBL30047446 | 0.78 | NR3C2 (0.44) | NR3C2NR3C1KCNH2 | |
| Hydrochloric Acid SCHEMBL23857692 | 0.78 | NR3C2 (0.44) | NR3C2NR3C1KCNH2 | |
| SCHEMBL23857622 | 0.77 | NR3C2 (0.44) | NR3C2NR3C1KCNH2 | |
| SCHEMBL23857638 | 0.76 | NR3C2 (0.45) | NR3C2NR3C1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126855-A1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-02-08 | — | — | EP | disclosed |
| CN-115298176-A | Compounds and their use in the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-11-04 | — | — | CN | disclosed |