Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16180195 | 1.00 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL16180193 | 1.00 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL30046981 | 1.00 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL15791849 | 0.94 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL15791847 | 0.94 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL30047331 | 0.94 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL15791867 | 0.94 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL15791813 | 0.93 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL15791816 | 0.93 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL19510094 | 0.91 | NR3C2 (0.57) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126855-A1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-02-08 | — | — | EP | disclosed |
| CN-115298176-A | Compounds and their use in the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-11-04 | — | — | CN | disclosed |