Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | PTAFR | P25105 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24814745 | 1.00 | OGA (0.32) | OGAPTGDR2PTAFR | |
| SCHEMBL24814753 | 0.87 | — | — | |
| SCHEMBL30047498 | 0.87 | — | — | |
| SCHEMBL24814739 | 0.86 | — | — | |
| SCHEMBL24815176 | 0.85 | — | — | |
| SCHEMBL30048086 | 0.85 | — | — | |
| SCHEMBL23601058 | 0.78 | MAPT (0.34) | PTGDR2PTAFR | |
| SCHEMBL23601469 | 0.77 | NQO2 (0.32) | PTAFR | |
| SCHEMBL23601349 | 0.74 | PTAFR (0.31) | PTAFR | |
| SCHEMBL23577576 | 0.74 | PTAFR (0.32) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359415-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022271684-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |