Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 4/20 | 0.34 |
| ▸ | USP7 | Q93009 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23857539 | 1.00 | USP8 (0.34) | USP8USP7RECQLKDM4EALDH1A1 | |
| SCHEMBL23856825 | 0.80 | CHEK1 (0.30) | — | |
| SCHEMBL30047126 | 0.80 | CHEK1 (0.30) | — | |
| SCHEMBL30048454 | 0.77 | RECQL (0.33) | RECQLKDM4EALDH1A1HPGD | |
| SCHEMBL23857222 | 0.77 | RECQL (0.33) | RECQLKDM4EALDH1A1HPGD | |
| SCHEMBL23856482 | 0.75 | — | — | |
| SCHEMBL30047585 | 0.74 | CA12 (0.36) | KDM4E | |
| SCHEMBL23871569 | 0.74 | CA12 (0.36) | KDM4E | |
| SCHEMBL23856822 | 0.73 | — | — | |
| SCHEMBL30048678 | 0.72 | JAK3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298176-A | Compounds and their use in the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-11-04 | — | — | CN | disclosed |