SCHEMBL300488

SCHEMBL300488

CC12CCC(C1)C(C)(C)[C@H]2NC(=O)Oc1nn(-c2ccc(F)cc2F)c2c1CCCCC2Cc1cccc(F)c1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 18/20 0.53
CNR1 P21554 12/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300476 0.95 CNR2 (0.55) CNR2CNR1
SCHEMBL300695 0.91 CNR1 (0.46) CNR2CNR1
SCHEMBL176487 0.89 CNR2 (0.65) CNR2CNR1
SCHEMBL300681 0.87 CNR2 (0.40) CNR2CNR1
SCHEMBL300530 0.85 CNR1 (0.48) CNR2CNR1
SCHEMBL10080069 0.84 CNR2 (0.68) CNR2CNR1
SCHEMBL176550 0.83 CNR2 (0.68) CNR2CNR1
SCHEMBL300365 0.80 CNR2 (0.41) CNR2CNR1
SCHEMBL176565 0.80 CNR2 (0.54) CNR2CNR1
SCHEMBL13147592 0.80 CNR2 (0.61) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937259-B1 HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2011-11-23 EP claimed