Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 15/20 | 0.54 |
| ▸ | EGFR | P00533 | 11/20 | 0.54 |
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | FECH | P22830 | 1/20 | 0.52 |
| ▸ | MYH14 | Q7Z406 | 1/20 | 0.52 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24809491 | 1.00 | ERBB2 (0.54) | ERBB2EGFRNQO2FECHMYH14 | |
| SCHEMBL31476030 | 0.91 | ERBB2 (0.53) | ERBB2EGFRNQO2FECHMYH14 | |
| SCHEMBL30050657 | 0.91 | EGFR (0.53) | ERBB2EGFR | |
| SCHEMBL24807827 | 0.91 | EGFR (0.53) | ERBB2EGFR | |
| SCHEMBL26108457 | 0.90 | ERBB2 (0.60) | ERBB2EGFRNQO2FECHMYH14 | |
| SCHEMBL29309573 | 0.90 | EGFR (0.53) | ERBB2EGFRNQO2FECHMYH14 | |
| SCHEMBL30051115 | 0.89 | ERBB2 (0.53) | ERBB2EGFRNQO2FECHMYH14 | |
| SCHEMBL24809511 | 0.89 | ERBB2 (0.54) | ERBB2EGFR | |
| SCHEMBL25430697 | 0.89 | EGFR (0.53) | ERBB2EGFRNQO2FECHMYH14 | |
| SCHEMBL30576304 | 0.89 | EGFR (0.53) | ERBB2EGFRNQO2FECHMYH14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022269531-A1 | HER2 MUTATION INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2022-12-29 | — | — | WO | disclosed |