Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 13/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | USP2 | O75604 | 6/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27162246 | 1.00 | CYP3A4 (0.43) | CYP3A4CYP2D6CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL27162591 | 0.96 | SMN1; SMN2 (0.40) | CYP3A4CYP2D6CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30049542 | 0.96 | SMN1; SMN2 (0.40) | CYP3A4CYP2D6CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL27162042 | 0.92 | CYP3A4 (0.47) | CYP3A4CYP2D6CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30049081 | 0.92 | CYP3A4 (0.47) | CYP3A4CYP2D6CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30050034 | 0.91 | SMN1; SMN2 (0.43) | CYP3A4CYP2D6ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27162198 | 0.91 | SMN1; SMN2 (0.43) | CYP3A4CYP2D6ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30050705 | 0.91 | CYP3A4 (0.40) | CYP3A4CYP2D6CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL27162324 | 0.91 | CYP3A4 (0.40) | CYP3A4CYP2D6CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30049623 | 0.88 | CYP3A4 (0.56) | CYP3A4CYP2D6CYP1A2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4330248-A1 | PYRIDINE-SULFONAMIDE DERIVATIVES AS SIGMA LIGANDS | Acondicionamiento Tarrasense (ES) | 2024-03-06 | — | — | EP | claimed |
| WO-2022229405-A1 | PYRIDINE-SULFONAMIDE DERIVATIVES AS SIGMA LIGANDS | ACONDICIONAMIENTO TARRASENSE (ES) | 2022-11-03 | — | — | WO | claimed |
| EP-4330248-A1 | PYRIDINE-SULFONAMIDE DERIVATIVES AS SIGMA LIGANDS | Acondicionamiento Tarrasense (ES) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022229405-A1 | PYRIDINE-SULFONAMIDE DERIVATIVES AS SIGMA LIGANDS | ACONDICIONAMIENTO TARRASENSE (ES) | 2022-11-03 | — | — | WO | disclosed |