Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19417846 | 1.00 | MAPT (0.69) | MAPTHTTPOLBCYP1A2CYP2C9 | |
| SCHEMBL9425659 | 0.86 | MAPT (0.67) | MAPTHTTPOLBCYP1A2CYP2C9 | |
| SCHEMBL1710516 | 0.84 | MAPT (0.65) | MAPTHTTPOLBCYP1A2CYP2C9 | |
| SCHEMBL20189964 | 0.84 | MAPT (0.50) | MAPTHTTPOLBCYP1A2CYP2C9 | |
| SCHEMBL4555801 | 0.82 | SMN1; SMN2 (0.53) | MAPTHTTPOLBLMNAMAPK1 | |
| SCHEMBL20189765 | 0.82 | MAPT (0.49) | MAPTHTTPOLBCYP1A2CYP2C9 | |
| SCHEMBL15771279 | 0.82 | CYP3A4 (0.52) | MAPTHTTPOLBCYP1A2CYP2C9 | |
| SCHEMBL4437996 | 0.82 | MAPT (0.53) | MAPTHTTPOLBLMNAMAPK1 | |
| SCHEMBL15771015 | 0.81 | MAPT (0.48) | MAPTHTTPOLBCYP1A2CYP2C9 | |
| SCHEMBL20189504 | 0.80 | MAPT (0.47) | MAPTHTTPOLBCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110225912-B | GSK-3 inhibitors | 百时美施贵宝公司 | 2022-10-21 | — | — | CN | disclosed |