Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 1/20 | 1.00 |
| ▸ | MET | P08581 | 2/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.55 |
| ▸ | KDR | P35968 | 9/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317847 | 1.00 | DDR2 (1.00) | DDR2METPDGFRAKDRKDM4E | |
| SCHEMBL29318211 | 0.91 | DDR2 (0.83) | DDR2METPDGFRAKDRCSF1R | |
| SCHEMBL29317854 | 0.91 | DDR2 (0.83) | DDR2METPDGFRAKDRCSF1R | |
| SCHEMBL30050292 | 0.91 | DDR2 (0.83) | DDR2METPDGFRAKDRCSF1R | |
| SCHEMBL29317860 | 0.90 | DDR2 (0.82) | DDR2METPDGFRAKDRFGFR2 | |
| SCHEMBL30051291 | 0.90 | DDR2 (0.82) | DDR2METPDGFRAKDRCSF1R | |
| SCHEMBL30049816 | 0.90 | DDR2 (0.82) | DDR2METPDGFRAKDRFGFR2 | |
| SCHEMBL29186568 | 0.90 | DDR2 (0.82) | DDR2METPDGFRAKDRCSF1R | |
| SCHEMBL29186589 | 0.90 | DDR2 (0.82) | DDR2METPDGFRAKDRFGFR2 | |
| SCHEMBL30050295 | 0.90 | DDR2 (0.82) | DDR2METPDGFRAKDRFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4330233-A1 | PHENYL -O-QUINOLINE, QUINAZOLINE, THIENOPYRIDINE, THIENOPYRIMIDINE, PYRROLOPYRIDINE, PYRROLOPYRIMIDINE COMPOUNDS HAVING ANTICANCER ACTIVITY | Chengdu Anticancer Bioscience, Ltd. (CN) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022228549-A1 | PHENYL -O-QUINOLINE, QUINAZOLINE, THIENOPYRIDINE, THIENOPYRIMIDINE, PYRROLOPYRIDINE, PYRROLOPYRIMIDINE COMPOUNDS HAVING ANTICANCER ACTIVITY | Chengdu Anticancer Bioscience, Ltd. (CN) | 2022-11-03 | — | — | WO | disclosed |