Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA7 | P43166 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13286874 | 0.94 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2994752 | 0.91 | NSD2 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10784179 | 0.89 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2761252 | 0.87 | CA1 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18121547 | 0.87 | KMT2A (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18329185 | 0.86 | CA1 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18121554 | 0.86 | CA12 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2991344 | 0.85 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30674458 | 0.85 | NSD2 (0.71) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8204859 | 0.85 | NSD2 (0.71) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190856-A1 | Novel Polyhydroxylated Compounds as Fatty Acid Synthase (FASN) Inhibitors | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2010-07-29 | — | — | US | claimed |
| EP-2170802-A1 | NOVEL POLYHYDROXYLATED COMPOUNDS AS FATTY ACID SYNTHASE (FASN) INHIBITORS | Fundació Privada Institut d'Investigació Biomédica de Girona - Dr. Josep Trueta (ES) | 2010-04-07 | — | — | EP | claimed |
| WO-2009000864-A1 | NOVEL POLYHYDROXYLATED COMPOUNDS AS FATTY ACID SYNTHASE (FASN) INHIBITORS | FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ BIOMÈDICA DE GIRONA DR. JOSEP TRUETA (ES) | 2008-12-31 | — | — | WO | claimed |
| US-20100190856-A1 | Novel Polyhydroxylated Compounds as Fatty Acid Synthase (FASN) Inhibitors | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2010-07-29 | — | — | US | disclosed |
| US-20100190856-A1 | Novel Polyhydroxylated Compounds as Fatty Acid Synthase (FASN) Inhibitors | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2010-07-29 | — | — | US | disclosed |
| US-20100190856-A1 | Novel Polyhydroxylated Compounds as Fatty Acid Synthase (FASN) Inhibitors | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2010-07-29 | — | — | US | disclosed |
| EP-2170802-A1 | NOVEL POLYHYDROXYLATED COMPOUNDS AS FATTY ACID SYNTHASE (FASN) INHIBITORS | Fundació Privada Institut d'Investigació Biomédica de Girona - Dr. Josep Trueta (ES) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009000864-A1 | NOVEL POLYHYDROXYLATED COMPOUNDS AS FATTY ACID SYNTHASE (FASN) INHIBITORS | FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ BIOMÈDICA DE GIRONA DR. JOSEP TRUETA (ES) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000864-A1 | NOVEL POLYHYDROXYLATED COMPOUNDS AS FATTY ACID SYNTHASE (FASN) INHIBITORS | FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ BIOMÈDICA DE GIRONA DR. JOSEP TRUETA (ES) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190856-A1 | Novel Polyhydroxylated Compounds as Fatty Acid Synthase (FASN) Inhibitors | FASN, SCD, FADS2 | CA12 4827/4885CA1 4396/4885CA2 4131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.