Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 16/20 | 0.51 |
| ▸ | CNR2 | P34972 | 7/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176562 | 0.88 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL300471 | 0.86 | CNR1 (0.46) | CNR1CNR2PTGS2PTGS1 | |
| SCHEMBL300552 | 0.85 | CNR1 (0.62) | CNR1CNR2 | |
| SCHEMBL300514 | 0.84 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL300680 | 0.84 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL300477 | 0.83 | CNR1 (0.71) | CNR1CNR2 | |
| SCHEMBL300670 | 0.83 | CNR1 (0.71) | CNR1CNR2 | |
| SCHEMBL300725 | 0.79 | CNR1 (0.78) | CNR1CNR2 | |
| SCHEMBL300494 | 0.79 | CNR1 (0.78) | CNR1CNR2 | |
| SCHEMBL300523 | 0.79 | CNR1 (0.65) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |