Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 18/20 | 0.48 |
| ▸ | CNR2 | P34972 | 7/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300714 | 1.00 | CNR1 (0.48) | CNR1CNR2IDO1NR1H4 | |
| SCHEMBL300471 | 0.89 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL300391 | 0.88 | CNR1 (0.51) | CNR1CNR2 | |
| SCHEMBL300493 | 0.88 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL300719 | 0.88 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL176617 | 0.87 | CNR1 (0.61) | CNR1CNR2 | |
| SCHEMBL176598 | 0.87 | CNR1 (0.61) | CNR1CNR2 | |
| SCHEMBL300652 | 0.87 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL300547 | 0.87 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL300684 | 0.83 | CNR1 (0.60) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |