Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 1.00 |
| ▸ | IL17A | Q16552 | 1/20 | 1.00 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.63 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347132 | 1.00 | BRD4 (1.00) | BRD4IL17AHDAC1HDAC6HDAC3 | |
| SCHEMBL378226 | 0.99 | BRD4 (0.98) | BRD4IL17AHDAC1HDAC6HDAC3 | |
| SCHEMBL378016 | 0.99 | BRD4 (0.98) | BRD4IL17AHDAC1HDAC6HDAC3 | |
| SCHEMBL377761 | 0.98 | BRD4 (0.96) | BRD4IL17AHDAC1HDAC6HDAC3 | |
| SCHEMBL377826 | 0.95 | BRD4 (0.91) | BRD4IL17AHDAC1HDAC6HDAC3 | |
| SCHEMBL377797 | 0.95 | BRD4 (0.90) | BRD4IL17AHDAC1HDAC6HDAC3 | |
| SCHEMBL377723 | 0.94 | BRD4 (0.88) | BRD4IL17AHDAC1HDAC6HDAC3 | |
| SCHEMBL349172 | 0.92 | BRD4 (0.85) | BRD4IL17AHDAC1HDAC6HDAC3 | |
| SCHEMBL30053181 | 0.92 | BRD4 (0.85) | BRD4IL17AHDAC1HDAC6HDAC3 | |
| SCHEMBL378069 | 0.90 | BRD4 (0.81) | BRD4IL17AHDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114984016-A | Compositions and methods for treating complement-associated diseases | 雷斯韦洛吉克斯公司 | 2022-09-02 | — | — | CN | claimed |
| CN-114984016-A | Compositions and methods for treating complement-associated diseases | 雷斯韦洛吉克斯公司 | 2022-09-02 | — | — | CN | disclosed |