Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.73 |
| ▸ | IL17A | Q16552 | 1/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.70 |
| ▸ | PARP1 | P09874 | 2/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.69 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.69 |
| ▸ | BRD1 | O95696 | 1/20 | 0.53 |
| ▸ | BRD2 | P25440 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146056 | 1.00 | BRD4 (0.73) | BRD4IL17AHDAC1PARP1HDAC3 | |
| SCHEMBL17930617 | 0.91 | BRD4 (0.74) | BRD4IL17AHDAC1PARP1HDAC3 | |
| Apabetalone SCHEMBL145019 | 0.91 | BRD4 (0.84) | BRD4IL17AHDAC1PARP1HDAC3 | |
| SCHEMBL30052937 | 0.91 | BRD4 (0.74) | BRD4IL17AHDAC1PARP1HDAC3 | |
| SCHEMBL347354 | 0.91 | BRD4 (0.74) | BRD4IL17AHDAC1PARP1HDAC3 | |
| Apabetalone SCHEMBL29352238 | 0.91 | BRD4 (0.84) | BRD4IL17AHDAC1PARP1HDAC3 | |
| SCHEMBL23442956 | 0.90 | BRD4 (0.73) | BRD4IL17AHDAC1PARP1HDAC3 | |
| SCHEMBL10279774 | 0.90 | BRD4 (0.73) | BRD4IL17AHDAC1PARP1HDAC3 | |
| SCHEMBL151927 | 0.90 | BRD4 (0.73) | BRD4IL17AHDAC1PARP1HDAC3 | |
| SCHEMBL21524680 | 0.89 | BRD4 (0.72) | BRD4IL17AHDAC1PARP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114984016-A | Compositions and methods for treating complement-associated diseases | 雷斯韦洛吉克斯公司 | 2022-09-02 | — | — | CN | claimed |
| CN-107252429-B | Novel anti-inflammatory agent | 雷斯韦洛吉克斯公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-114984016-A | Compositions and methods for treating complement-associated diseases | 雷斯韦洛吉克斯公司 | 2022-09-02 | — | — | CN | disclosed |