Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.60 |
| ▸ | PARP2 | Q9UGN5 | 10/20 | 0.60 |
| ▸ | PARP6 | Q2NL67 | 2/20 | 0.56 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.56 |
| ▸ | TNKS | O95271 | 1/20 | 0.56 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27169460 | 1.00 | PARP1 (0.60) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL27169477 | 0.88 | PARP1 (0.65) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL29397527 | 0.88 | PARP1 (0.65) | PARP1PARP2PARP6PARP3TNKS | |
| Hydrochloric Acid SCHEMBL30054423 | 0.88 | PARP1 (0.58) | PARP1PARP2PARP6PARP3TNKS | |
| Hydrochloric Acid SCHEMBL27169429 | 0.88 | PARP1 (0.58) | PARP1PARP2PARP6PARP3TNKS | |
| Hydrochloric Acid SCHEMBL31312822 | 0.87 | PARP1 (0.64) | PARP1PARP2PARP6PARP3TNKS | |
| Hydrochloric Acid SCHEMBL27169435 | 0.87 | PARP1 (0.64) | PARP1PARP2PARP6PARP3TNKS | |
| Hydrochloric Acid SCHEMBL30053682 | 0.87 | PARP1 (0.64) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL27169515 | 0.83 | PARP1 (0.55) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL30874292 | 0.83 | PARP1 (0.67) | PARP1PARP2PARP6PARP3TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334314-A1 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | Nuvation Bio Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| CN-117580839-A | Anti-cancer nuclear hormone receptor targeting compounds | 诺维逊生物股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| WO-2022235585-A1 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | NUVATION BIO INC. (US) | 2022-11-10 | — | — | WO | disclosed |