Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30054700 | 0.83 | — | — | |
| SCHEMBL30053857 | 0.82 | — | — | |
| SCHEMBL26503987 | 0.82 | PDE9A (0.33) | — | |
| SCHEMBL30054478 | 0.78 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL23846923 | 0.76 | OPRL1 (0.32) | — | |
| SCHEMBL30054485 | 0.73 | UGT2B17 (0.47) | EPAS1CYP11B1CYP11B2 | |
| SCHEMBL30055213 | 0.72 | — | — | |
| SCHEMBL23832873 | 0.72 | — | — | |
| SCHEMBL30054188 | 0.71 | — | — | |
| SCHEMBL10300799 | 0.70 | PARP1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298165-A | Tetralin and tetrahydroquinoline compounds as HIF-2 alpha inhibitors | 艾库斯生物科学有限公司 | 2022-11-04 | — | — | CN | disclosed |