Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | PI4KA | P42356 | 3/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.48 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.46 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 2/20 | 0.44 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | AHCY | P23526 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3005664 | 0.85 | CCNE1 (0.49) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL3005457 | 0.80 | ADORA2A (0.48) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2999182 | 0.79 | CCNE1 (0.36) | ADORA2AADORA1METTL3METTL14 | |
| SCHEMBL2995698 | 0.78 | HSP90AB1 (0.42) | — | |
| SCHEMBL3000253 | 0.77 | PDE4A (0.38) | — | |
| SCHEMBL3293432 | 0.75 | FGFR1 (0.47) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2988384 | 0.75 | CDK1 (0.36) | ADORA1 | |
| SCHEMBL2996742 | 0.74 | HDAC1 (0.43) | — | |
| SCHEMBL2996932 | 0.73 | CYP1A2 (0.40) | ADORA2AADORA1ALDH1A1 | |
| SCHEMBL2904496 | 0.71 | FGFR1 (0.61) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |