Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 10/20 | 1.00 |
| ▸ | FLT1 | P17948 | 9/20 | 1.00 |
| ▸ | FLT3 | P36888 | 9/20 | 1.00 |
| ▸ | CSF1R | P07333 | 8/20 | 1.00 |
| ▸ | LCK | P06239 | 8/20 | 1.00 |
| ▸ | FGFR1 | P11362 | 6/20 | 1.00 |
| ▸ | AURKA | O14965 | 6/20 | 1.00 |
| ▸ | ABL1 | P00519 | 6/20 | 1.00 |
| ▸ | FYN | P06241 | 6/20 | 1.00 |
| ▸ | LYN | P07948 | 6/20 | 1.00 |
| ▸ | BLK | P51451 | 6/20 | 1.00 |
| ▸ | GSK3B | P49841 | 5/20 | 1.00 |
| ▸ | FGFR3 | P22607 | 5/20 | 1.00 |
| ▸ | PLK4 | O00444 | 5/20 | 1.00 |
| ▸ | NTRK1 | P04629 | 5/20 | 1.00 |
| ▸ | RPS6KB1 | P23443 | 5/20 | 1.00 |
| ▸ | MARK3 | P27448 | 5/20 | 1.00 |
| ▸ | RPS6KA3 | P51812 | 5/20 | 1.00 |
| ▸ | NEK2 | P51955 | 5/20 | 1.00 |
| ▸ | LIMK1 | P53667 | 5/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546436 | 1.00 | KIT (1.00) | KITFLT1FLT3CSF1RLCK | |
| Bromide SCHEMBL5436521 | 0.99 | KIT (0.98) | KITFLT1FLT3CSF1RLCK | |
| Hydrochloric Acid SCHEMBL4301600 | 0.99 | KIT (0.98) | KITFLT1FLT3CSF1RLCK | |
| Alcohol SCHEMBL3238965 | 0.97 | FLT1 (0.93) | KITFLT1FLT3CSF1RLCK | |
| SCHEMBL3567468 | 0.91 | KIT (0.83) | KITFLT1FLT3CSF1RLCK | |
| SCHEMBL4473254 | 0.91 | KIT (0.83) | KITFLT1FLT3CSF1RLCK | |
| SCHEMBL4487735 | 0.90 | KIT (0.82) | KITFLT1FLT3CSF1RLCK | |
| SCHEMBL4486498 | 0.90 | KIT (0.82) | KITFLT1FLT3CSF1RLCK | |
| SCHEMBL4478648 | 0.89 | FLT1 (0.79) | KITFLT1FLT3CSF1RLCK | |
| SCHEMBL4478281 | 0.88 | KIT (0.78) | KITFLT1FLT3CSF1RLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4663249-A2 | DRUG THERAPY TO INHIBIT CHEMOTHERAPY-INDUCED ADVERSE EFFECTS AND RELATED PHARMACEUTICAL COMPOSITIONS, DIAGNOSTICS, SCREENING TECHNIQUES AND KITS | Yale University, Inc. (US) | 2025-12-17 | — | — | EP | disclosed |
| EP-4186501-B1 | DRUG THERAPY TO INHIBIT CHEMOTHERAPY-INDUCED ADVERSE EFFECTS AND RELATED PHARMACEUTICAL COMPOSITIONS, DIAGNOSTICS, SCREENING TECHNIQUES AND KITS | YALE UNIV INC (US) | 2025-07-30 | — | — | EP | disclosed |
| EP-4334305-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2024-03-13 | — | — | EP | disclosed |
| EP-4186501-A1 | DRUG THERAPY TO INHIBIT CHEMOTHERAPY-INDUCED ADVERSE EFFECTS AND RELATED PHARMACEUTICAL COMPOSITIONS, DIAGNOSTICS, SCREENING TECHNIQUES AND KITS | Yale University, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| WO-2022236101-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY (US) | 2022-11-10 | — | — | WO | disclosed |
| WO-2022216717-A1 | CITRON KINASE INHIBITORS | THE CLEVELAND CLINIC FOUNDATION (US) | 2022-10-13 | — | — | WO | disclosed |