Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.42 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300365 | 0.93 | CNR2 (0.41) | CNR2CNR1APP | |
| SCHEMBL300504 | 0.92 | CNR2 (0.42) | CNR2CNR1TAS1R3TAS1R1 | |
| SCHEMBL300681 | 0.88 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL176436 | 0.87 | CNR2 (0.47) | CNR2CNR1TAS1R3TAS1R1 | |
| SCHEMBL300538 | 0.81 | CNR2 (0.39) | CNR2CNR1TAS1R3TAS1R1 | |
| SCHEMBL300671 | 0.81 | CNR2 (0.39) | CNR2CNR1TAS1R3TAS1R1 | |
| SCHEMBL300530 | 0.80 | CNR1 (0.48) | CNR2CNR1 | |
| SCHEMBL176428 | 0.79 | CNR2 (0.46) | CNR2CNR1 | |
| SCHEMBL176495 | 0.79 | CNR2 (0.51) | CNR2CNR1 | |
| SCHEMBL300685 | 0.79 | CNR2 (0.41) | CNR2CNR1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |