Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MRE11 | P49959 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23705549 | 0.86 | HDAC6 (0.52) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23705551 | 0.86 | HDAC6 (0.52) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23705746 | 0.85 | HDAC6 (0.47) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23705742 | 0.85 | HDAC6 (0.47) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23705752 | 0.80 | MRE11 (0.52) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23705751 | 0.80 | MRE11 (0.52) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21224180 | 0.77 | HDAC6 (0.70) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21224178 | 0.77 | HDAC6 (0.70) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28519111 | 0.75 | HDAC6 (0.59) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21224494 | 0.75 | HDAC6 (0.67) | HDAC6HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097096-A2 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |