Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.53 |
| ▸ | AR | P10275 | 5/20 | 0.49 |
| ▸ | HPGDS | O60760 | 2/20 | 0.46 |
| ▸ | IL2 | P60568 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30741714 | 0.87 | CRBN (0.69) | CRBNDDB1ARHPGDS | |
| SCHEMBL23729513 | 0.87 | CRBN (0.69) | CRBNDDB1ARHPGDS | |
| SCHEMBL23705532 | 0.85 | CRBN (0.66) | CRBNDDB1ARHPGDS | |
| SCHEMBL30066277 | 0.84 | CRBN (0.63) | CRBNDDB1ARHPGDS | |
| SCHEMBL27131517 | 0.84 | CRBN (0.60) | CRBNDDB1ARHPGDS | |
| SCHEMBL26702915 | 0.83 | CRBN (0.74) | CRBNDDB1ARHPGDS | |
| SCHEMBL29683622 | 0.83 | CRBN (0.63) | CRBNDDB1ARHPGDS | |
| SCHEMBL30066259 | 0.83 | CRBN (0.63) | CRBNDDB1ARHPGDS | |
| SCHEMBL31722340 | 0.82 | CRBN (0.60) | CRBNDDB1ARHPGDS | |
| SCHEMBL26063876 | 0.82 | CRBN (0.57) | CRBNDDB1ARHPGDSITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097096-A2 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |