Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 20/20 | 1.00 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.79 |
| ▸ | GAK | O14976 | 3/20 | 0.79 |
| ▸ | CIT | O14578 | 3/20 | 0.79 |
| ▸ | MYLK2 | Q9H1R3 | 3/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.79 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.79 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.79 |
| ▸ | BMP2K | Q9NSY1 | 4/20 | 0.72 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.72 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.72 |
| ▸ | JAK2 | O60674 | 1/20 | 0.72 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.72 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.72 |
| ▸ | DMPK | Q09013 | 1/20 | 0.72 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | PRKCB | P05771 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20154451 | 1.00 | AAK1 (1.00) | AAK1MKNK1GAKCITMYLK2 | |
| SCHEMBL17155450 | 1.00 | AAK1 (1.00) | AAK1MKNK1GAKCITMYLK2 | |
| SCHEMBL30578941 | 1.00 | AAK1 (1.00) | AAK1MKNK1GAKCITMYLK2 | |
| SCHEMBL17143553 | 0.92 | AAK1 (0.85) | AAK1MKNK1GAKCITMYLK2 | |
| SCHEMBL20738221 | 0.90 | AAK1 (1.00) | AAK1MKNK1GAKCITMYLK2 | |
| SCHEMBL17155570 | 0.90 | AAK1 (1.00) | AAK1MKNK1GAKCITMYLK2 | |
| SCHEMBL29400561 | 0.90 | AAK1 (1.00) | AAK1MKNK1GAKCITMYLK2 | |
| SCHEMBL17155656 | 0.90 | AAK1 (1.00) | AAK1MKNK1GAKCITMYLK2 | |
| SCHEMBL17155448 | 0.90 | AAK1 (1.00) | AAK1MKNK1GAKCITMYLK2 | |
| SCHEMBL29400172 | 0.90 | AAK1 (1.00) | AAK1MKNK1GAKCITMYLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250262197-A1 | COMPOUNDS AND METHODS FOR TREATING CHEMOTHERAPY-INDUCED PAIN | LEXICON PHARMACEUTICALS, INC. (US) | 2025-08-21 | — | — | US | disclosed |
| CN-118973576-A | Compounds and methods for treating spasticity | 莱西肯医药有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-115484951-A | AAK1 inhibitors for the treatment of viral infections | 莱西肯医药有限公司 | 2022-12-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250262197-A1 | COMPOUNDS AND METHODS FOR TREATING CHEMOTHERAPY-INDUCED PAIN | PNCK, CAMKK1, CAMK2G | AAK1 33/4885MKNK1 194/4885GAK 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.