Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30060144 | 1.00 | HDAC1 (0.45) | HDAC1HDAC6FAAHTYRO3PIM1 | |
| Trifluoroacetic Acid SCHEMBL30230512 | 0.97 | HDAC1 (0.43) | HDAC1HDAC6FAAHTYRO3PIM1 | |
| Trifluoroacetic Acid SCHEMBL30062036 | 0.97 | HDAC1 (0.43) | HDAC1HDAC6FAAHTYRO3PIM1 | |
| SCHEMBL24072828 | 0.88 | HDAC1 (0.52) | HDAC1HDAC6KMT2AALDH1A1HPGD | |
| SCHEMBL25838395 | 0.88 | HDAC1 (0.52) | HDAC1HDAC6KMT2AALDH1A1HPGD | |
| SCHEMBL24073562 | 0.88 | HDAC1 (0.52) | HDAC1HDAC6KMT2AALDH1A1HPGD | |
| SCHEMBL27418092 | 0.88 | HDAC1 (0.52) | HDAC1HDAC6KMT2AALDH1A1HPGD | |
| SCHEMBL25211891 | 0.87 | HDAC1 (0.40) | HDAC1HDAC6FAAHPIM1 | |
| Trifluoroacetic Acid SCHEMBL30370026 | 0.85 | HDAC1 (0.49) | HDAC1HDAC6 | |
| Trifluoroacetic Acid SCHEMBL30474049 | 0.85 | HDAC1 (0.49) | HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461340-A | N-cyanopyrrolidines having activity as USP30 inhibitors | 特殊治疗有限公司 | 2022-12-09 | — | — | CN | disclosed |