⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20404268 | 1.00 | — | — | |
| SCHEMBL10229515 | 0.89 | CD44 (0.48) | — | |
| SCHEMBL29661353 | 0.85 | CD44 (0.53) | — | |
| SCHEMBL353635 | 0.85 | CD44 (0.53) | — | |
| SCHEMBL751800 | 0.85 | BCL2L1 (0.56) | — | |
| SCHEMBL30513686 | 0.85 | BCL2L1 (0.56) | — | |
| SCHEMBL1280654 | 0.84 | CD44 (0.48) | — | |
| SCHEMBL7952487 | 0.83 | BCL2L1 (0.54) | — | |
| Hydrochloric Acid SCHEMBL11381455 | 0.83 | CD44 (0.52) | — | |
| SCHEMBL3801550 | 0.83 | BCL2L1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635373-B | Amide derivatives and use thereof | 康百达（四川）生物医药科技有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-122036626-A | Pyrimidine-2 (1H) -ketone derivative, pharmaceutical composition and application thereof | 上海青润医药科技有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-116635374-B | Amide derivatives and use thereof | 康百达（四川）生物医药科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-118290330-A | Amide derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-117247393-A | Amide derivative, preparation method thereof and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-117105890-A | Amide derivative, preparation method thereof and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-116804018-A | Amide derivative, preparation method thereof and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-116635373-A | Amide derivatives and use thereof | 成都百裕制药股份有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116635374-A | Amide derivatives and use thereof | 成都百裕制药股份有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116041702-A | Shape memory polyimide molding powder, preparation method and application thereof, and shape memory polyimide three-dimensional block material | 中国科学院兰州化学物理研究所 | 2023-05-02 | — | — | CN | disclosed |
| WO-2022237780-A1 | AMIDE DERIVATIVE AND USE THEREOF | 成都百裕制药股份有限公司 | 2022-11-17 | — | — | WO | disclosed |
| WO-2022237782-A1 | AMIDE DERIVATIVE AND APPLICATION THEREOF | 成都百裕制药股份有限公司 | 2022-11-17 | — | — | WO | disclosed |