Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23816103 | 1.00 | BTK (0.40) | BTKLCKRETKDR | |
| SCHEMBL28915454 | 0.91 | BTK (0.41) | BTKLCK | |
| SCHEMBL30063526 | 0.88 | BTK (0.38) | BTKLCK | |
| SCHEMBL23816195 | 0.88 | BTK (0.38) | BTKLCK | |
| SCHEMBL30063492 | 0.87 | BTK (0.49) | BTKLCKRETKDR | |
| SCHEMBL23816181 | 0.87 | BTK (0.49) | BTKLCKRETKDR | |
| SCHEMBL23816562 | 0.81 | BTK (0.40) | BTKLCK | |
| SCHEMBL28915536 | 0.79 | BTK (0.39) | BTKLCK | |
| SCHEMBL28915495 | 0.78 | BTK (0.51) | BTKLCK | |
| SCHEMBL23816332 | 0.77 | BTK (0.48) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335376-A | Degradation of Bruton's Tyrosine Kinase (BTK) by conjugation of BTK inhibitor with E3 ligase ligand and methods of use thereof | 百济神州有限公司 | 2022-11-11 | — | — | CN | disclosed |