⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11858888 | 0.88 | — | — | |
| SCHEMBL4735180 | 0.82 | — | — | |
| SCHEMBL14642656 | 0.80 | — | — | |
| SCHEMBL6676256 | 0.75 | — | — | |
| SCHEMBL1564365 | 0.73 | — | — | |
| SCHEMBL24907016 | 0.71 | — | — | |
| SCHEMBL1565127 | 0.71 | — | — | |
| SCHEMBL16160802 | 0.71 | — | — | |
| SCHEMBL4490176 | 0.71 | — | — | |
| SCHEMBL1564363 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129080-A1 | COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | MITOKININ, INC. (US) | 2025-04-24 | — | — | US | disclosed |
| EP-3822274-B1 | SYNTHETIC INTERMEDIATES USEFUL FOR PREPARING SUBSTITUTED AMINOPURINE COMPOUNDS | SIGNAL PHARM LLC (US) | 2024-03-06 | — | — | EP | disclosed |
| CN-117327671-A | Novel ketoreductase mutant and preparation method and application thereof | 上海泓博尚奕药物技术有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-117327671-A | Novel ketoreductase mutant and preparation method and application thereof | 上海泓博尚奕药物技术有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-116199806-A | Coordination precipitation polymerization method for olefin polymerization and obtained polyolefin | 中国石油化工股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| US-20230158035-A1 | SUBSTITUTED AMINOPURINE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2023-05-25 | — | — | US | disclosed |
| US-11590139-B2 | Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith | SIGNAL PHARMACEUTICALS, LLC (US) | 2023-02-28 | — | — | US | disclosed |
| WO-2023023670-A1 | COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | MITOKININ, INC. (US) | 2023-02-23 | — | — | WO | disclosed |
| WO-2023023670-A1 | COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | MITOKININ, INC. (US) | 2023-02-23 | — | — | WO | disclosed |
| CN-113248506-A | Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith | 西格诺药品有限公司 | 2021-08-13 | — | — | CN | disclosed |
| US-20100152178-A1 | IMIDAZOLE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100003724-A1 | CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID | TriLink Bio Technologies | 2010-01-07 | — | — | US | disclosed |
| WO-2009117278-A2 | PROCESSES FOR PREPARING (AMINO-PYRAZOLOPYRIDINYL)METHOXY SUBSTITUTED BIARYL ETHERS | MERCK & CO., INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| EP-2090570-A1 | IMIDAZOLE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-08-19 | — | — | EP | disclosed |
| CN-101511796-A | Imidazole derivative | KYOWA HAKKO KOGYO KK (JP) | 2009-08-19 | — | — | CN | disclosed |
| US-20090005269-A1 | Novel Silane Compounds and Their Use in Functionalizing Solid Supports and Immobilizing Biological Molecules on These Supports | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-01-01 | — | — | US | disclosed |
| EP-0581464-A1 | Ester derivatives and pharmaceutical compositions containing them | ZENECA LIMITED (GB) | 1994-02-02 | — | — | EP | disclosed |
| EP-0275431-B1 | NOVEL ANTHRACYCLINE DERIVATIVES, A PROCESS FOR PREPARING SAME AND THEIR USE AS MEDICAMENTS | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1992-09-23 | — | — | EP | disclosed |
| EP-0335369-A2 | New anthracycline derivatives and processes for the preparation of the same | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-10-04 | — | — | EP | disclosed |
| EP-0275431-A1 | Novel anthracycline derivatives, a process for preparing same and their use as medicaments | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1988-07-27 | — | — | EP | disclosed |