Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.50 |
| ▸ | SKP1 | P63208 | 2/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4195090 | 0.85 | USP2 (0.46) | CKS1BSKP1SKP2USP2SMN1; SMN2 | |
| SCHEMBL1017250 | 0.76 | PIK3CA (0.52) | SMN1; SMN2MAPTRECQLMTORPIK3R1 | |
| SCHEMBL26034741 | 0.76 | CKS1B (0.56) | CKS1BSKP1SKP2SMN1; SMN2MAPT | |
| SCHEMBL4214586 | 0.76 | USP2 (0.43) | USP2SMN1; SMN2MAPTRECQLMTOR | |
| SCHEMBL9948010 | 0.76 | HTR2C (0.54) | USP2SMN1; SMN2MAPTMTORPIK3R1 | |
| SCHEMBL30063682 | 0.76 | MAPT (0.52) | CKS1BSKP1SKP2USP2SMN1; SMN2 | |
| SCHEMBL21591643 | 0.76 | CKS1B (0.55) | CKS1BSKP1SKP2SMN1; SMN2MAPT | |
| SCHEMBL30064995 | 0.75 | MAPT (0.51) | CKS1BSKP1SKP2USP2SMN1; SMN2 | |
| SCHEMBL1017921 | 0.74 | MAPT (0.77) | USP2SMN1; SMN2MAPTMTORPIK3R1 | |
| SCHEMBL4205087 | 0.74 | MAP4K4 (0.48) | CKS1BSKP1SKP2MAPTGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4352062-A2 | 5-HT2A AND/OR 5-HT2C RECEPTOR AGONISTS | Diamond Therapeutics Inc. (CA) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022234339-A2 | 5-HT2A AND/OR 5-HT2C RECEPTOR AGONISTS | DIAMOND THERAPEUTICS INC. (CA) | 2022-11-10 | — | — | WO | disclosed |