Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 7/20 | 0.34 |
| ▸ | CD69 | Q07108 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26117219 | 1.00 | BTK (0.34) | BTKCD69CYP3A4CYP2C9 | |
| SCHEMBL26117214 | 1.00 | BTK (0.34) | BTKCD69CYP3A4CYP2C9 | |
| SCHEMBL30063454 | 0.89 | BTK (0.35) | BTKCD69CYP3A4CYP2C9 | |
| SCHEMBL26117243 | 0.89 | BTK (0.35) | BTKCD69CYP3A4CYP2C9 | |
| SCHEMBL26117250 | 0.89 | BTK (0.35) | BTKCD69CYP3A4CYP2C9 | |
| SCHEMBL23816490 | 0.88 | BTK (0.36) | BTKCD69CYP3A4CYP2C9 | |
| SCHEMBL26115607 | 0.88 | BTK (0.36) | BTKCD69CYP3A4CYP2C9 | |
| SCHEMBL30063479 | 0.87 | BTK (0.43) | BTK | |
| SCHEMBL26116685 | 0.87 | BTK (0.43) | BTK | |
| SCHEMBL26114427 | 0.80 | HDAC4 (0.35) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335376-A | Degradation of Bruton's Tyrosine Kinase (BTK) by conjugation of BTK inhibitor with E3 ligase ligand and methods of use thereof | 百济神州有限公司 | 2022-11-11 | — | — | CN | disclosed |