Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23816017 | 1.00 | BTK (0.45) | BTKLCKPLAT | |
| SCHEMBL23816197 | 0.92 | BTK (0.52) | BTKLCK | |
| Hydrochloric Acid SCHEMBL30063459 | 0.92 | BTK (0.52) | BTKLCK | |
| Hydrochloric Acid SCHEMBL26114720 | 0.92 | BTK (0.52) | BTKLCK | |
| SCHEMBL30063476 | 0.87 | BTK (0.44) | BTKLCKPLAT | |
| SCHEMBL23816068 | 0.87 | BTK (0.44) | BTKLCKPLAT | |
| SCHEMBL26114595 | 0.87 | BTK (0.46) | BTKLCK | |
| Hydrochloric Acid SCHEMBL30064492 | 0.87 | BTK (0.46) | BTKLCK | |
| Hydrochloric Acid SCHEMBL26113873 | 0.87 | BTK (0.46) | BTKLCK | |
| SCHEMBL23816261 | 0.82 | BTK (0.44) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791426-A | (R) -glutarimide CRBN ligands and methods of use | 百济神州有限公司 | 2024-10-18 | — | — | CN | disclosed |
| EP-4359403-A1 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BeiGene Switzerland GmbH (CH) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022268052-A9 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2022268052-A1 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BEIGENE, LTD. (KY) | 2022-12-29 | — | — | WO | disclosed |
| CN-115335376-A | Degradation of Bruton's Tyrosine Kinase (BTK) by conjugation of BTK inhibitor with E3 ligase ligand and methods of use thereof | 百济神州有限公司 | 2022-11-11 | — | — | CN | disclosed |