Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 14/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21292661 | 1.00 | GAA (0.41) | GAATHRBGBA1GBA2POLB | |
| SCHEMBL3317512 | 1.00 | GAA (0.41) | GAATHRBGBA1GBA2POLB | |
| SCHEMBL16279687 | 1.00 | GAA (0.41) | GAATHRBGBA1GBA2POLB | |
| SCHEMBL25237187 | 0.88 | POLB (0.46) | GAATHRBGBA1GBA2POLB | |
| SCHEMBL3360203 | 0.82 | GBA1 (0.42) | GAATHRBGBA1GBA2 | |
| SCHEMBL16277708 | 0.82 | PLG (0.32) | — | |
| SCHEMBL13942058 | 0.82 | GBA1 (0.42) | GAATHRBGBA1GBA2 | |
| SCHEMBL15186923 | 0.82 | GBA1 (0.42) | GAATHRBGBA1GBA2 | |
| SCHEMBL3360199 | 0.82 | GBA1 (0.42) | GAATHRBGBA1GBA2 | |
| SCHEMBL13032050 | 0.79 | GBA1 (0.42) | GAATHRBGBA1GBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087573-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-11-16 | — | — | EP | disclosed |