SCHEMBL30065286

SCHEMBL30065286

O=C(O)N1CC(F)[C@H](CO)C1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22554851 1.00 DPP4 (0.30) DPP4
SCHEMBL22208153 1.00 DPP4 (0.30) DPP4
SCHEMBL14801540 1.00 DPP4 (0.30) DPP4
SCHEMBL2908778 0.84 POLB (0.32)
SCHEMBL3372261 0.84 POLB (0.32)
SCHEMBL2908775 0.84 POLB (0.32)
SCHEMBL23825814 0.82 DPP4 (0.31) DPP4
SCHEMBL6120413 0.82 DPP4 (0.31) DPP4
SCHEMBL28250719 0.82 GABRR1 (0.38) DPP4
SCHEMBL14480018 0.79 DPP4 (0.41) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4087573-A1 KRAS G12C INHIBITORS Mirati Therapeutics, Inc. (US) 2022-11-16 EP disclosed