Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GRB2 | P62993 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523139 | 0.94 | MDM2 (0.53) | PTPN1MDM2TLR2MDM4TP53 | |
| SCHEMBL23728660 | 0.94 | MDM2 (0.53) | PTPN1MDM2TLR2MDM4TP53 | |
| SCHEMBL17697136 | 0.94 | MDM2 (0.53) | PTPN1MDM2TLR2MDM4TP53 | |
| SCHEMBL23728661 | 0.94 | MDM2 (0.53) | PTPN1MDM2TLR2MDM4TP53 | |
| SCHEMBL29978024 | 0.92 | PTPN1 (0.54) | PTPN1MDM2MDM4TP53GRB2 | |
| SCHEMBL120511 | 0.92 | MDM2 (0.55) | MDM2TLR2MDM4TP53 | |
| SCHEMBL29352017 | 0.92 | MDM2 (0.55) | MDM2TLR2MDM4TP53 | |
| SCHEMBL29768913 | 0.92 | MDM2 (0.55) | MDM2TLR2MDM4TP53 | |
| SCHEMBL117964 | 0.92 | MDM2 (0.55) | MDM2TLR2MDM4TP53 | |
| SCHEMBL29792372 | 0.92 | MDM2 (0.55) | MDM2TLR2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113501871-B | Method for preparing darunavagon by combining solid phase with liquid phase | 汉肽生物医药集团有限公司 | 2022-10-28 | — | — | CN | disclosed |