⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335737 | 0.72 | — | — | |
| SCHEMBL8426535 | 0.69 | — | — | |
| SCHEMBL735065 | 0.67 | — | — | |
| SCHEMBL4965995 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL27522184 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL22836740 | 0.65 | — | — | |
| SCHEMBL708427 | 0.62 | — | — | |
| Sulfurous Acid SCHEMBL29281765 | 0.62 | — | — | |
| SCHEMBL3795102 | 0.62 | — | — | |
| SCHEMBL493409 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856711-B1 | SYNTHETIC METHOD FOR THE PREPARATION OF AN HYDRAZINE COMPOUND | MEREO BIOPHARMA 1 LTD (GB) | 2022-11-16 | — | — | EP | claimed |
| US-11649213-B2 | Synthetic method for the preparation of a 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol compound | MEREO BIOPHARMA 1 LIMITED (GB) | 2023-05-16 | — | — | US | disclosed |
| EP-3856721-B1 | SYNTHETIC METHOD FOR THE PREPARATION OF A 3-[5-AMINO-4-(3-CYANOBENZOYL)-PYRAZOL COMPOUND | MEREO BIOPHARMA 1 LTD (GB) | 2023-03-29 | — | — | EP | disclosed |
| EP-3856711-B1 | SYNTHETIC METHOD FOR THE PREPARATION OF AN HYDRAZINE COMPOUND | MEREO BIOPHARMA 1 LTD (GB) | 2022-11-16 | — | — | EP | disclosed |