Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 20/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23496010 | 0.98 | KDM1A (1.00) | KDM1A | |
| SCHEMBL30067548 | 0.98 | KDM1A (1.00) | KDM1A | |
| SCHEMBL20512397 | 0.98 | KDM1A (1.00) | KDM1A | |
| Maleic Acid SCHEMBL30067608 | 0.95 | KDM1A (0.91) | KDM1A | |
| Fumaric Acid SCHEMBL31000952 | 0.95 | KDM1A (0.91) | KDM1A | |
| SCHEMBL30067552 | 0.94 | KDM1A (0.93) | KDM1A | |
| SCHEMBL30067611 | 0.93 | KDM1A (0.91) | KDM1A | |
| SCHEMBL27171696 | 0.92 | KDM1A (0.88) | KDM1A | |
| SCHEMBL31000932 | 0.92 | KDM1A (0.88) | KDM1A | |
| SCHEMBL20512631 | 0.91 | KDM1A (1.00) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228438-A1 | SOLID FORMS OF SALTS OF 4-[5-[(3S)-3-AMINOPYRROLIDINE-1-CARBONYL]-2-[2-FLUORO-4-(2- HYDROXY-2-ETHYLPROPYL)PHENYL]PHENYL]-2-FLUORO-BENZONITRILE | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-11 | — | — | US | claimed |
| EP-4337638-A1 | SOLID FORMS OF SALTS OF 4-[5-[(3S)-3-AMINOPYRROLIDINE-1-CARBONYL]-2-[2-FLUORO-4-(2-HYDROXY-2-ETHYLPROPYL)PHENYL]PHENYL]-2-FLUORO-BENZONITRILE | Astex Pharmaceuticals, Inc. (US) | 2024-03-20 | — | — | EP | claimed |
| WO-2022240886-A1 | SOLID FORMS OF SALTS OF 4-[5-[(3S)-3-AMINOPYRROLIDINE-1-CARBONYL]-2-[2-FLUORO-4-(2-HYDROXY-2-ETHYLPROPYL)PHENYL]PHENYL]-2-FLUORO-BENZONITRILE | ASTEX PHARMACEUTICALS, INC. (US) | 2022-11-17 | — | — | WO | claimed |
| US-20240228438-A1 | SOLID FORMS OF SALTS OF 4-[5-[(3S)-3-AMINOPYRROLIDINE-1-CARBONYL]-2-[2-FLUORO-4-(2- HYDROXY-2-ETHYLPROPYL)PHENYL]PHENYL]-2-FLUORO-BENZONITRILE | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228438-A1 | SOLID FORMS OF SALTS OF 4-[5-[(3S)-3-AMINOPYRROLIDINE-1-CARBONYL]-2-[2-FLUORO-4-(2- HYDROXY-2-ETHYLPROPYL)PHENYL]PHENYL]-2-FLUORO-BENZONITRILE | AFF4, SKP1, CYP3A4 | KDM1A 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.