Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.60 |
| ▸ | PKM | P14618 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16037476 | 1.00 | MAPT (0.60) | MAPTPKMPOLBKMT2AMEN1 | |
| SCHEMBL1699987 | 1.00 | MAPT (0.60) | MAPTPKMPOLBKMT2AMEN1 | |
| SCHEMBL1699969 | 0.94 | MAPT (0.57) | MAPTPKMPOLBKMT2AMEN1 | |
| SCHEMBL30075042 | 0.94 | MAPT (0.57) | MAPTPKMPOLBKMT2AMEN1 | |
| SCHEMBL1699967 | 0.94 | MAPT (0.57) | MAPTPKMPOLBKMT2AMEN1 | |
| SCHEMBL1700196 | 0.94 | MAPT (0.57) | MAPTPKMPOLBKMT2AMEN1 | |
| SCHEMBL16038843 | 0.94 | MAPT (0.61) | MAPTPKMPOLBKMT2AMEN1 | |
| SCHEMBL523815 | 0.93 | MAPT (0.59) | MAPTPKMPOLBKMT2AMEN1 | |
| SCHEMBL29387647 | 0.93 | MAPT (0.59) | MAPTPKMPOLBKMT2AMEN1 | |
| SCHEMBL16038582 | 0.92 | MAPT (0.63) | MAPTPKMPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115484933-A | Hot melt extrusion solid dispersions containing BCL2 inhibitors | 广州麓鹏制药有限公司 | 2022-12-16 | — | — | CN | disclosed |